US-Engineered · ISO 9001:2015 · Since 2005
Low Differential Pressure Transducers & Transmitters for HVAC/R and
Industrial Applications
We don’t make level sensors. We don’t make temperature sensors. We make only low differential
pressure sensors — and we make the best. Founded by an MIT engineering professor with 18+ patents in
capacitive sensor technology.
Patents in Sensor Technology
Years of Precision Engineering
Certified Manufacturing

Precision Pressure Sensors Built for Industry
From cost-effective HVAC/R transmitters to high-accuracy cleanroom transducers — every Alpha
sensor is engineered around our patented capacitive sensing technology.

Cost-Effective Differential Pressure Transmitter
Reliable, economical pressure sensing for HVAC/R and building
automation applications. Compact design, easy installation.

Differential Pressure Transmitter with Digital Display
On-board LCD display for local readout. Ideal for cleanroom
monitoring and critical environment applications.

Stainless Steel Wet/Wet Differential Pressure Transducer
All-stainless steel construction for demanding industrial
environments. Compatible with liquid and gas media on both ports.

Ultra-Low Range Differential Pressure Transducer
Exceptional sensitivity down to 0.05″ WC. Purpose-built for
semiconductor cleanrooms and pharmaceutical isolators.
Engineered for Critical Environments Worldwide
Every industry has unique pressure monitoring requirements. We engineer solutions specific to
your application — not one-size-fits-all products.
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HVAC/R
Duct pressure, filter monitoring, building automation, VAV control
Cleanrooms
Room pressurization, ISO class monitoring, laminar flow verification
Pharmaceutical
Isolator pressure, sterile suite monitoring, USP 797/800 compliance
Semiconductor
Fab pressure cascading, mini-environment control, AMC monitoring
Data Centers
Hot/cold aisle containment, under-floor pressure, airflow management
Animal Husbandry
Barn ventilation, ammonia monitoring, negative-pressure isolation
MIT Roots. Precision Engineering. American Manufacturing.
Founded in 2005 by an MIT engineering professor, Alpha Instruments was built on a single conviction: that differential pressure measurement could be more accurate, more reliable, and
more affordable.
Two decades and 18+ patents later, we remain fiercely specialized. Every
sensor we ship is built around our proprietary capacitive sensing element — a technology we invented,
refined, and perfected in our Acton, Massachusetts facility.
We are ISO 9001:2015 certified. Our products carry CE, RoHS, and UL marks.
And we back every instrument with a 2-year warranty and lifetime technical support.
Built to the Highest Standards
MIT-Founded
Technology rooted in academic research. Founded by a professor who pioneered capacitive MEMS pressure sensing.
18+ US & International Patents
Core capacitive sensor technology protected by a robust IP portfolio — including US, EU, and China patents.
ISO 9001:2015 Certified
Quality management system audited annually. Every sensor calibrated against NIST-traceable
standards.
CE · RoHS · UL Recognized
Global compliance marks for EU, North America, and Asia-Pacific markets. Ready for export
worldwide.
US-Engineered & Manufactured
R&D, engineering, and final calibration performed in Acton, MA. Global manufacturing
with US quality oversight.
Lifetime Technical Support
Application engineers — not call center staff — answer your technical questions. Free for
the life of the product.
2-Year Warranty
Every Alpha sensor is backed by an industry-leading 2-year warranty against defects in
materials and workmanship.
Rapid Global Delivery
Warehouses in North America, Europe, and Asia-Pacific. Most orders ship within 48 hours —
ready for urgent projects.
What Our Customers Say
“We replaced our legacy pressure sensors with Alpha’s Model 165 on
47 semiconductor cleanroom skids. Accuracy improved by 40%, and the capacitive technology eliminated the
drift issues we fought for years. Their application engineers worked alongside our team for two weeks
during commissioning. That level of support is rare.”
“We install Alpha transmitters in every data center we commission.
The dual 4-20mA + RS485 output means we get analog to the BMS and digital to our analytics platform from
one device. And at their price point, there’s nothing else that matches the accuracy. Our standard spec
now calls for Alpha on all differential pressure applications.”
“We’ve been using Alpha pressure transmitters in our pharmaceutical
cleanrooms for over 5 years. The Model 165’s ultra-low range capability is perfect for USP 797 compliance monitoring. Zero drift in 3 years of continuous operation. Our FDA auditors specifically noted the
quality of our pressure monitoring system.”
“Alpha’s sensor-to-price ratio is unmatched. We evaluated six brands for our building automation retrofit program and Alpha won on accuracy, delivery time, and cost.
Switching to Model 162 with RS485 gave us digital data we never had before — our energy savings alone
paid for the sensors in 8 months.”
Latest from the Alpha Instruments Knowledge Base
Technical articles, application guides, and industry insights — written by our engineering
team.

Cleanroom Pressure Cascading: A
Complete Design Guide for Engineers
How to design multi-zone pressure cascades that meet ISO 14644
standards. Includes step-by-step calculations and real-world examples from pharmaceutical and
semiconductor facilities.

Why Your Differential
Pressure Sensor is Drifting — and How to Fix It
Zero-point drift is the most common field service call for
pressure transmitters. Understand the 4 root causes and how to resolve each one — from thermal effects to moisture ingress.

Pressure
Transducer vs. Transmitter: What’s the Difference?
The terms are often used interchangeably — but the distinction
matters for your application. Compare output signals, wiring requirements, noise immunity, and cost
across technologies.
2026 Product Catalog &
Selection Guide
Complete specifications for all Models 161–175. Includes application notes, wiring diagrams,
dimensional drawings, and an industry-by-industry product selector matrix.
Instruments
Frequently Asked Questions
A pressure transducer converts pressure into an unamplified electrical
signal (typically mV/V or 0-5V). A pressure transmitter includes signal conditioning
electronics that amplify and convert the signal to an industry-standard output like 4-20mA or 0-10V —
making it suitable for long cable runs and noisy industrial environments. All Alpha “transmitters”
include built-in amplification; our “transducers” are unamplified sensor elements for OEM
integration.
Select a sensor whose full-scale range is 120-150% of your maximum expected operating
pressure. For example, if you need to measure up to 1.0″ WC, choose a 0-1.5″ WC or 0-2.0″ WC range.
Oversizing too much (e.g., using a 0-10″ WC sensor for a 0-0.5″ WC application) reduces effective
resolution and increases relative error. Our application engineers can help you select the optimal range
— contact us with your requirements.
4-20mA (current loop) is preferred for industrial environments: it’s immune to electrical noise, supports cable runs up to 1,000+ feet, and the 4mA “live zero” allows the
controller to detect a broken wire (0mA = fault). 0-10V (voltage output) is simpler to
interface with data loggers and PLC analog input cards, but cable length should be kept under 50 feet to
avoid voltage drop. We offer both on most models — specify at order.
Alpha recommends annual calibration for most applications. Critical environments
(pharmaceutical GMP, semiconductor cleanrooms, hospital isolation rooms) may require semi-annual or
quarterly calibration per regulatory requirements. All Alpha sensors ship with a NIST-traceable
calibration certificate. We offer factory recalibration services with a 5-business-day turnaround — contact our service department for RMA.
Let’s Find the Right Sensor for Your Application
Tell us your pressure range, media, output preference, and quantity — our engineering team will
respond with a tailored recommendation and quote within one business day.
